Universities and Institutes of Italy

Universities and Institutes of Italy

Structural And Functional Neural Alterations Induced By Polyfluoroalkyl Substances (Pfas) Investigated In Vitro In Human Brain Organoids

Italy

Expired

12 Sep 2023

Job Information

Organisation/Company

Università degli Studi di Padova - Dipartimento di Fisica e Astronomia

Research Field

Physics

Researcher Profile

Recognised Researcher (R2)

Leading Researcher (R4)

First Stage Researcher (R1)

Established Researcher (R3)

Country

Italy

Application Deadline

25 Sep 2023 - 23:59 (UTC)

Type of Contract

To be defined

Job Status

Not Applicable

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Per- and polyfluoroalkyl substances (PFAS) are a group of manufactured chemicals that are widely used to make various types of everyday products. Once ingested or inhaled they accumulate in cell membranes causing disease, including cancer, metabolic, neurological and reproductive disorders. This project aims to continue our previous study in dopaminergic neurons using a human three-dimensional model (organoid) that reproduces the area of the brain richest in this type of neurons, which is involved in the development of Parkinson's disease. The selected candidate will work with state-of-the-art biophysical and biological facilities, including electrophysiology (patch- clamp and multielectrode arrays) and fluorescence microscopy (wide-field, confocal, 2-photon, STED). The project aims to identify structural and functional neuronal network alterations which underlie the toxic effect of PFAS in the midbrain.

Requirements Additional Information

Eligibility criteria

the selection takes plase through the evaluation of the titles, scientific and professional CV, academic/scientific publications and reference letter

Eligible destination country/ies for fellows:

  • Italy
  • Eligibility of fellows: country/ies of residence:

  • International
  • Eligibility of fellows: nationality/ies:

  • International
  • Selection process

    The applications will be valued by a referre committee, designed by the Director of the structure and composed by three members belongin to the scientific area of the research project, one of them is normally the scientific responsaible of the scientific project

    Website for additional job details

    https:// www. dfa.unipd.it/servizi/amministrazione-trasparente/bandi-di- concorso/b…

    Work Location(s)

    Number of offers available

    1
    

    Company/Institute

    Università degli Studi di Padova - Dipartimento di Fisica e Astronomia
    

    Country

    Italy
    
    Where to apply

    Website

    https: // pica.cineca.it/unipd/

    Contact

    City

    Padova

    Website

    https:// www. dfa.unipd.it/servizi/amministrazione-trasparente/bandi-di- concorso/bandi-didattica-ricerca-e-altre-tipologie/assegni-di- ricerca/selezioni-aperte-o-in-svolgimento/

    STATUS: EXPIRED

    Job details

    Title

    Structural And Functional Neural Alterations Induced By Polyfluoroalkyl Substances (Pfas) Investigated In Vitro In Human Brain Organoids

    Employer

    Universities and Institutes of Italy

    Location

    Italy

    Published

    September 13, 2023

    Application deadline

    September 25, 2023

    Job type

    Postdoc,Research

    Field

    Agricultural Science,Biology,Chemistry,Engineering,Physics,Space Science