University of Glassgow

University of Glassgow

Senior Cryo-EM Data Scientist

United Kingdom

Closing in 6 days

Senior Cryo-EM Data Scientist

Job Purpose

The postholder will join us at the Scottish Centre for Macromolecular Imaging (SCMI, https: // www. ). The SCMI is a consortium of 4 Scottish universities with an interest in cryo-EM – University of Dundee, University of Edinburgh, University of St Andrews, and University of Glasgow, where we are based. We deliver high-quality single particle and tomography data to users from our consortium partners and externally using our flagship CRYO ARM 300 microscope. We also run a sample preparation laboratory and microscopes for negative staining and cryo- screening. These are mostly used by users from University of Glasgow in our role as their local cryo-EM facility but are also available for external use. The work is varied, with many projects and users coming through the facility. On average, we have around 30 active users each year, from total beginners through to experienced principal investigators.

The primary role of this post will be to support SCMI users with their data processing tasks, from data delivery post-acquisition through to deposition and archiving. Example activities include delivering user training in image processing, implementing data processing pipelines and managing our data storage array.

The postholder will be a motivated scientist with a proven interest and aptitude for biological imaging and structural biology.

Main Duties and Responsibilities

1. Manage the flow of data generated by SCMI users, setting up workflows for on-the-fly processing, delivery of data to end-users and eventual deposition.

2. Plan and deliver training courses in image processing and onboarding for users new to command line usage, HPC and job scheduling software.

3. Provide expert advice and assistance to users encountering difficult image processing problems.

4. Manage the facility's data storage and back-up capabilities, ensuring users remove or archive their data as appropriate.

5. Contribute to managing the HPC cluster, liaising with our internal systems administrator and external service contract provider.

6. Advise on future equipment requirements and upgrades.

7. Take an active role in organising symposia and other SCMI-led events.

8. Contribute to the preparation of annual reports on SCMI performance for review by the external scientific advisory group.

9. Contribute to research publications in leading international journals and presentations at national and international conferences, thereby enhancing the reputation of the SCMI community, the CVR, the School, the College and the University

Please note that this job description is not exhaustive, and you may be required to undertake other relevant duties commensurate with the grading of the post. Activities may be subject to amendment over time as the role develops and/or priorities and requirements evolve.

Please note that as part of your application you must address and demonstrate how you meet EACH of the essential/desirable criteria. If you do not address each criterion in the format explained below you will not be shortlisted for interview.

Qualifications, Knowledge, Skills and Experience



A1 Ability to demonstrate the competencies required to undertake the duties associated with this level of post having acquired the necessary knowledge and skills in a similar role.

Or: Scottish Credit and Qualification Framework level 9 Ordinary Degree, Scottish Vocational Qualification level 4 or equivalent, in a relevant biological or physical science including professional accreditation with relevant formal training, and experience of personal development in a similar role.


B1 A postgraduate degree in a relevant biological or physical science.

Knowledge and Skills


C1 Knowledge of multiple software packages for cryo-EM single particle analysis.

C2 Skills in the use and management of Unix-based server systems, including job scheduling software.

C3 Knowledge of the principles and practice of cryo-EM.

C4 Excellent communication and interpersonal skills. C5 Highly motivated, ability to use initiative and quick to learn new techniques. C6 Appropriate workload and time management skills.


D1 Knowledge of image processing pipelines used in cryo-electron tomography and subtomogram averaging



E1 Experience of solving structures by cryo-EM single particle analysis

E2 Experience of managing and configuring workstations or clusters for research computing/image processing

E3 Experience of delivering training or teaching in small groups or 1-to-1

E4 Experience of trouble-shooting experiments.

E5 Experience in presenting research results to colleagues and peers.


F1 Experience operating a cryo-electron microscope

F2 Experience of working with hazard group 2 pathogens or above.

F3 Experience of processing cryo-electron tomography data

Additional Details

The post is full-time and open ended.

For enquiries regarding this post please contact the SCMI Facility Manager, Dr James Streetley via email [email protected]

Terms and Conditions

Salary will be Grade 7, £39,347 - £44,263 per annum.

This post is full time and open ended.

As part of Team UofG you will be a member of a world changing, inclusive community, which values ambition, excellence, integrity and curiosity.

As a valued member of our team, you can expect:

1 A warm welcoming and engaging organisational culture, where your talents are developed and nurtured, and success is celebrated and shared.

2 An excellent employment package with generous terms and conditions including 41 days of leave for full time staff, pension - pensions handbook https: // www., benefits and discount packages.

3 A flexible approach to working.

4 A commitment to support your health and wellbeing, including a free 6-month UofG Sport membership for all new staff joining the University https: // www.

We believe that we can only reach our full potential through the talents of all. Equality, diversity and inclusion are at the heart of our values. Applications are particularly welcome from across our communities and in particular people from the Black, Asian and Minority Ethnic (BAME) community, and other protected characteristics who are under-represented within the University. Read more on how the University promotes and embeds all aspects of equality and diversity within our community https: // www.

We endorse the principles of Athena Swan https: // www. and hold bronze, silver and gold awards across the University.

We are investing in our organisation, and we will invest in you too. Please visit our website https: // www. for more information.

Vacancy Ref : 145749 Close Date : 04-Jun-2024 23:45

Job details


Senior Cryo-EM Data Scientist


University of Glassgow


United Kingdom


May 08, 2024

Application deadline

June 04, 2024

Job type



Agricultural Science,Biology,Chemistry,Computer Science,Engineering,Physics

About the employer

The University of Glasgow was established in the year 1451 by papal bull. It is among the 4th ancient universities in Scotland and the fourth-oldest university in the USA. It was a part of the Scottish Enlightenment along with Edinburg, St. Andrews, and Aberdeen during the 18th century. Among the ancient universities in the UK, the University of Glasgow is one of the eight institutions that award undergraduate and graduate degrees in popular disciplines. The university comprises four colleges that include the College of Science & Engineering, College of Arts, College of Medical, Veterinary & Life Sciences, and College of Social Sciences.

The university is spread over different campuses. The main campus is the Gilmorehill campus situated in Hillhead. The campus in the Garscube Estate in Bearsden houses the Veterinary School and sports facilities of the university and Dental school, the medical section is taken care of at Gartnavel Royal Hospital located on Great Western Road. Moreover, the Crichton campus and the teaching center at the Queen Elizabeth University Hospital in Dumfries are jointly operated by the Open University, the University of the West of Scotland, and the University of Glasgow.

The University of Glasgow has 30,000 undergraduate and postgraduate students from over 140 countries worldwide. It is a major employer in the city of Glasgow with more than 8,000 staff, including more than 3,400 research and teaching staff. The university is a member of the prestigious Russell Group of leading UK research universities

The university has introduced the World-Changing Alumni award for celebrating the excellent performance of the notable alumni. The winners include Susanne Mitschke in 2017 and Matt Fountain in 2016. Some of the other notable alumni who are now being recognized by the world include the three Prime Ministers namely Bonar Law, Sir Henry Campbell-Bannerman, and William Lamb.

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