University of Leeds

University of Leeds

Research Fellow

Research Fellow

Are you an ambitious researcher looking for your next challenge? Do you have an established background in molecular virology? Do you want to further your career in one of the UKs leading research intensive Universities?

Two research fellow positions are available in the laboratory of Professor Mark Harris, funded by a Wellcome Discovery Award. We recently made the exciting discovery of a role for the kinase PKR and the down-stream transcription factor IRF1 in inducing expression of proteins that block virus assembly (DOI: 10.1371/journal.ppat.1010812), uncovering a hitherto unrecognised aspect of innate antiviral immunity. These positions will focus on identifying and characterising these novel antiviral effectors, initially using hepatitis C virus as a model system, but also evaluating effects on other pathogenic viruses such as Chikungunya virus and SARS-CoV-2. The project will initially involve transcriptomic analysis to identify genes regulated by PKR/IRF1, followed by investigation of their potential role in blocking assembly of infectious virus particles. The positions provide an opportunity to conduct ground-breaking research into the host response to virus infection and would suit individuals who have experience in working with pathogenic viruses in high containment, working with RNA and proven ability to generate and interpret ‘omics data. The successful applicants will join a large, interdisciplinary laboratory shared between multiple investigators and working on a range of viruses.

To explore the post further or for any queries you may have, please contact:

Professor Mark Harris

Tel: +44 (0)113 343 5632

Email: [email protected]

Location: Leeds - Main Campus

Faculty/Service: Faculty of Biological Sciences School/Institute: School of Molecular & Cellular Biology Category: Research Grade: Grade 7 Salary: £37,099 to £44,263 per annum Working Time: 100% Post Type: Full Time Contract Type: Fixed Term (Available on a fixed-term basis for 3 years in the first instance) Release Date: Tuesday 30 April 2024 Closing Date: Tuesday 28 May 2024 Reference: FBSMB1277 Downloads: Candidate Brief

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Job details

Title

Research Fellow

Employer

University of Leeds

Location

United Kingdom

Published

May 01, 2024

Application deadline

May 28, 2024

Job type

Postdoc,Research

Field

Biology,Chemistry,Medicine,Physics

About the employer

The University of Leeds is a public research university in Leeds, West Yorkshire, England. It was established in 1874 as the Yorkshire College of Science. In 1884 it merged with the Leeds School of Medicine (established 1831) and was renamed Yorkshire College. It became part of the federal Victoria University in 1887, joining Owens College (which became the University of Manchester) and University College Liverpool (which became the University of Liverpool). In 1904 a royal charter was granted to the University of Leeds by King Edward VII.

The university has 36,330 students, the 5th largest university in the UK (out of 169). From 2006 to present, the university has consistently been ranked within the top 5 (alongside the University of Manchester, Manchester Metropolitan University, the University of Nottingham and the University of Edinburgh) in the United Kingdom for the number of applications received. Leeds had an income of £789.6 million in 2019/20, of which £139.9 million was from research grants and contracts. The university has financial endowments of £82.1 million (2019–20), ranking outside the top ten British universities by financial endowment.

Notable alumni include current Leader of the Labour Party Keir Starmer, former Secretary of State Jack Straw, former co-chairman of the Conservative Party Sayeeda Warsi, Piers Sellers (NASA astronaut) and six Nobel laureates.

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