University of Oxford

University of Oxford

Postdoctoral Researcher

Postdoctoral Researcher

Jenner Institute, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ

We are seeking to appoint an enthusiastic and motivated Postdoctoral Researcher to join the Malaria Group in the Jenner Institute at the Nuffield Department of Medicine. The research groups at the Jenner Institute are focused on developing innovative vaccine candidates against the malaria parasite ( Plasmodium vivax and Plasmodium Falciparum ), testing them in pre-clinical studies with an aim to progress the most promising candidates to clinical trials.

This is an incredibly exciting opportunity to get involved in an innovative project. You will work in the molecular design of vaccines, such as VLP, subunit, viral-vectored or mRNA platforms, and be involved in the early stages of pre-clinical vaccine development exploring the immunogenicity of such vaccine developments in pre-clinical models. To succeed in this role, you will need to have experience working with animal models.

You will develop protocols and perform a range of experimental techniques, such as molecular cloning, cells transfection, microbial and mammalian cell culture, protein expression and chromatography purification, and immunological techniques (e.g. ELISA. ELISpot, Immunostaining, WB, and Flow Cytometry), and characterisation by different microscopy techniques. You will be gathering and analysing scientific data from a variety of sources, including review of the literature and data generated in-house and by the wider consortium. You will perform research work to a high standard, produce and maintain clear experimental plans, laboratory records, and generate reports.

It is essential that you hold a PhD/DPhil (or close to completion) in Biochemistry, Molecular Biology, Vaccinology or related field, with a keen interest in malaria and immunology of infectious diseases. You will be responsible for managing your own research and administrative activities and provide guidance/supervision as required to less experienced members of the research group, including research assistants, technicians, PhD, and project students.

You will have relevant proven wet-lab experience in mRNA biology, biogenesis, biosynthesis, and modifications for de novo mRNA synthesis, as well as good interpersonal and organisational skills. You will possess sufficient specialist knowledge in cellular and molecular biology, with experience working with DNA, in vitro transcription, RNA, and biochemistry modification of nucleotide molecules and demonstrate the ability to design, clone, and transfect expression plasmids and explore antigen expression in cell lines.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

This position is offered full time on a fixed term contract for 12 months in the first instance and is funded by the UK Research and Innovation/European Commission.

Only applications received before 12 midday on 8 April 2024 will be considered. Please quote 171719 on all correspondence.

Contact Person : Kristina Limbu Vacancy ID : 171719 Contact Phone : 01865617971 Closing Date & Time : 08-Apr-2024 12:00 Pay Scale : STANDARD GRADE 7 Contact Email : [email protected] Salary (£) : Grade 7: Salary in range £36,024 - £44,263 per annum

Job details

Title

Postdoctoral Researcher

Employer

University of Oxford

Location

United Kingdom

Published

March 26, 2024

Application deadline

April 08, 2024

Job type

Postdoc

Field

Biology,Chemistry,Medicine,Physics

About the employer

The University of Oxford is the oldest university in the English-speaking world, and is actually so ancient that its founding date is unknown – though it is thought that teaching took place there as early as the 11th century. It’s located in and around the medieval city center of Oxford, dubbed “the dreaming city of spires” by the 19th century poet Matthew Arnold, and comprises 44 colleges and halls as well as the largest library system in the UK. 

There are 22,000 students at Oxford in total, around half of whom are undergraduates, while 40 per cent are international students. A quarter of the city of Oxford’s residents are students, giving the city the youngest population in the UK. 

The University of Oxford does not have a main campus, its buildings and facilities instead being scattered around the medieval city center. Its colleges each have a distinctive character and traditions often dating back centuries. Colleges are self-governing institutions to which students usually apply directly. There are four academic divisions within Oxford University: Humanities, Mathematical, Physical and Life Sciences; Medical Sciences; and Social Sciences. The university’s particular strength is the sciences, and it is ranked number one in the world for medicine.

Oxford is a youthful and cosmopolitan city with plenty to see and do. There are dozens of historic and iconic buildings, including the Bodleian Libraries, Ashmolean Museum, Sheldonian Theatre, the cathedral, and the colleges themselves.  Students can choose to spend their time studying or avail themselves of the many extracurricular activities available. There’s a strong musical life at Oxford, with clubs and societies spanning all genres, from jazz, through to classical and folk. Oxford is also ranked highly for sport, with its top rowers taking part every year in the world-famous boat race with the University of Cambridge on the River Thames. Drama lovers are also well catered for, with one of the largest and most vibrant university drama scenes in the country.

Oxford has an alumni network of over 250,000 individuals, including more than 120 Olympic medalists, 26 Nobel Prize winners, seven poets laureate, and over 30 modern world leaders (including Bill Clinton, Aung San Suu Kyi, Indira Ghandi and 26 UK Prime Ministers). 

It has a friendly rivalry with Cambridge for the title of best university in the UK and is regularly ranked as being one of the top three universities in the world. Notable Oxford thinkers and scientists include Tim Berners-Lee, Stephen Hawking and Richard Dawkins.

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