University of Oxford

University of Oxford

Postdoctoral Researcher

United Kingdom

Closing in 7 days

Postdoctoral Researcher

Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DU

About the role

Working with Prof. Peter McHugh's research group to contribute to the study of DNA repair.

The post holder will be responsible for characterising repair factors through structural biology techniques, with a focus on cryo-electron microscopy. Ideal candidates should have expertise in molecular cloning, protein expression, purification, and structural methods, preferably in crystallography and electron microscopy. Knowledge of DNA modification enzymes and a background in DNA damage and repair fields are highly desirable.

Your responsibilities encompass testing hypotheses, managing academic research, developing scientific techniques, characterizing nucleases, staying updated on DNA repair advancements, and contributing to projects and grant proposals. You'll attend meetings, present reports, engage in scientific presentations, write for publication, and ensure compliance with safety protocols. Additionally, you'll manage lab equipment, provide guidance to team members, train juniors, and participate in public engagement activities.

The post will be based at the Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DU , and is offered on a full-time basis, fixed-term for 2 years in first instance.

About you

You will be required to have research experience in molecular cloning, cell culturing, cryo-electron microscopy, X-ray crystallography, and protein/complex characterization. A strong record of publishing in reputable journals and contributing to grant proposals is essential. Your role will involve managing research projects, mentoring junior researchers, collaborating internally and externally, and organizing and prioritizing work independently. Excellent written and oral communication skills, including presenting at international symposia and to non-specialist audiences, are also crucial.

Applicants should hold a PhD (or be near to completion) in structural biology molecular biology or biochemistry.

Application Process

You will be required to upload a supporting statement (setting out how you meet the selection criteria), a curriculum vitae and the names and contact details of two referees as part of your online application.

Only applications received before noon on Thursday, 29th February 2024 can be considered.

Committed to equality and valuing diversity

Contact Person : HR Officer Vacancy ID : 170882 Contact Phone : Closing Date & Time : 29-Feb-2024 12:00 Pay Scale : STANDARD GRADE 7 Contact Email : [email protected] Salary (£) : 36024 - 44263

Job details


Postdoctoral Researcher


University of Oxford


United Kingdom


February 06, 2024

Application deadline

February 29, 2024

Job type




About the employer

The University of Oxford is the oldest university in the English-speaking world, and is actually so ancient that its founding date is unknown – though it is thought that teaching took place there as early as the 11th century. It’s located in and around the medieval city center of Oxford, dubbed “the dreaming city of spires” by the 19th century poet Matthew Arnold, and comprises 44 colleges and halls as well as the largest library system in the UK. 

There are 22,000 students at Oxford in total, around half of whom are undergraduates, while 40 per cent are international students. A quarter of the city of Oxford’s residents are students, giving the city the youngest population in the UK. 

The University of Oxford does not have a main campus, its buildings and facilities instead being scattered around the medieval city center. Its colleges each have a distinctive character and traditions often dating back centuries. Colleges are self-governing institutions to which students usually apply directly. There are four academic divisions within Oxford University: Humanities, Mathematical, Physical and Life Sciences; Medical Sciences; and Social Sciences. The university’s particular strength is the sciences, and it is ranked number one in the world for medicine.

Oxford is a youthful and cosmopolitan city with plenty to see and do. There are dozens of historic and iconic buildings, including the Bodleian Libraries, Ashmolean Museum, Sheldonian Theatre, the cathedral, and the colleges themselves.  Students can choose to spend their time studying or avail themselves of the many extracurricular activities available. There’s a strong musical life at Oxford, with clubs and societies spanning all genres, from jazz, through to classical and folk. Oxford is also ranked highly for sport, with its top rowers taking part every year in the world-famous boat race with the University of Cambridge on the River Thames. Drama lovers are also well catered for, with one of the largest and most vibrant university drama scenes in the country.

Oxford has an alumni network of over 250,000 individuals, including more than 120 Olympic medalists, 26 Nobel Prize winners, seven poets laureate, and over 30 modern world leaders (including Bill Clinton, Aung San Suu Kyi, Indira Ghandi and 26 UK Prime Ministers). 

It has a friendly rivalry with Cambridge for the title of best university in the UK and is regularly ranked as being one of the top three universities in the world. Notable Oxford thinkers and scientists include Tim Berners-Lee, Stephen Hawking and Richard Dawkins.

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