University of Oxford

University of Oxford

Postdoctoral Research Scientist

United Kingdom

Closing soon

Postdoctoral Research Scientist

Centre for Medicines Discovery, NDM Research Building, Old Road Campus, Roosevelt Drive, Headington, Oxford, OX3 7FZ

We have an exciting opportunity for a Postdoctoral Research Scientist with expertise in endo-lysosomal biology and biochemical aspects of the ubiquitin- proteasome system (UPS)to join the Alzheimer's Research UK Oxford Drug Discovery Institute (ARUK-ODDI) based at the Centre for Medicines Discovery, Nuffield Department of Medicine.

You will be responsible for providing the experimental and analytical expertise required to prosecute target validation and drug discovery for mechanisms regulating endo-lysosomal functions and UPS-mediated proteostasis. You will develop screening assays, establish and pursue new scientific techniques. You will manage your own academic research and administrative activies, contribute ideas for new research projects and develop ideas for generating research income. You will conduct your own experimental work and provide expertise for the establishment and use of iPSC-derived neuronal cultures. Additionally, you will carry out collaborative projects with colleagues in partnering academic or industrial institutions and present research findings in discussions with collaborators.

To be successful in this role, you will hold a PhD/DPhil (or close to completion) in Cell Biology, Biochemistry or related subject, together with research experience relevant to the field of endo-lysosomes and protein degradation mechanisms. You will have previous experience in in vitro assay development to test the effect of pharmacological modulation. You will be able to manage in an organised manner the day-to-day tasks of independent experimental research. You will excellent communication skills including the ability to write test that can be published. Having experience in cellular pathology of Parkinson's or Alzheimer's disease is desirable.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

This position is offered full time on a fixed term contract until 21 March 2026 and is funded by the ONO Pharmaceuticals Co.

Only applications received before 12 midday on Friday 31 May 2024 will be considered. Please quote 172550 on all correspondence.

Contact Person : Kristina Limbu Vacancy ID : 172550 Contact Phone : 01865617971 Closing Date & Time : 31-May-2024 12:00 Pay Scale : STANDARD GRADE 7 Contact Email : [email protected] Salary (£) : Grade 7: Salary in range £36,024 - £44,263 per annum

Job details


Postdoctoral Research Scientist


University of Oxford


United Kingdom


May 03, 2024

Application deadline

May 31, 2024

Job type




About the employer

The University of Oxford is the oldest university in the English-speaking world, and is actually so ancient that its founding date is unknown – though it is thought that teaching took place there as early as the 11th century. It’s located in and around the medieval city center of Oxford, dubbed “the dreaming city of spires” by the 19th century poet Matthew Arnold, and comprises 44 colleges and halls as well as the largest library system in the UK. 

There are 22,000 students at Oxford in total, around half of whom are undergraduates, while 40 per cent are international students. A quarter of the city of Oxford’s residents are students, giving the city the youngest population in the UK. 

The University of Oxford does not have a main campus, its buildings and facilities instead being scattered around the medieval city center. Its colleges each have a distinctive character and traditions often dating back centuries. Colleges are self-governing institutions to which students usually apply directly. There are four academic divisions within Oxford University: Humanities, Mathematical, Physical and Life Sciences; Medical Sciences; and Social Sciences. The university’s particular strength is the sciences, and it is ranked number one in the world for medicine.

Oxford is a youthful and cosmopolitan city with plenty to see and do. There are dozens of historic and iconic buildings, including the Bodleian Libraries, Ashmolean Museum, Sheldonian Theatre, the cathedral, and the colleges themselves.  Students can choose to spend their time studying or avail themselves of the many extracurricular activities available. There’s a strong musical life at Oxford, with clubs and societies spanning all genres, from jazz, through to classical and folk. Oxford is also ranked highly for sport, with its top rowers taking part every year in the world-famous boat race with the University of Cambridge on the River Thames. Drama lovers are also well catered for, with one of the largest and most vibrant university drama scenes in the country.

Oxford has an alumni network of over 250,000 individuals, including more than 120 Olympic medalists, 26 Nobel Prize winners, seven poets laureate, and over 30 modern world leaders (including Bill Clinton, Aung San Suu Kyi, Indira Ghandi and 26 UK Prime Ministers). 

It has a friendly rivalry with Cambridge for the title of best university in the UK and is regularly ranked as being one of the top three universities in the world. Notable Oxford thinkers and scientists include Tim Berners-Lee, Stephen Hawking and Richard Dawkins.

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