Cancer Research UK

Cancer Research UK

Postdoctoral Research Scientist - Prof Vicky Cowling

United Kingdom

Closing in 8 days

Job details

Job title

Postdoctoral Research Scientist - Prof Vicky Cowling

Job reference

REQ00338

Date posted

13/05/2024

Application closing date

09/06/2024

Location

Glasgow

Salary

from £32,868 to £42,717 subject to experience, plus relocation allowance and visa costs if required.

Package

Blank

Contractual hours

35

Basis

Full time

Job category/type

Postdoctoral Fellows

Attachments

Blank

Job description

Prof Vicky Cowling

CRUK Scotland Lab: Gene Regulation

RNA cap regulation in brain cancers

Contract term: Fixed up to 6 years, subject to successful review at Year 3

About us

The CRUK Scotland Institute where the lab is based is a world leading cancer research institute, situated in the vibrant city of Glasgow in Scotland and hosting approximately 60 postdoctoral researcher scientists at any one time. It has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned in vivo modelling of tumour growth and metastasis.

Project outline

We are looking for a postdoctoral researcher to join us in the Cowling lab to investigate RNA cap regulation in brain cancers. How are the RNA capping enzymes regulated in neurons and in response to oncogenic pathways in glioblastoma cells? What is the impact of these mechanisms on gene regulation, cell function and differentiation? How does RNA cap regulation influence tumour formation and response to therapies? These experiments will be supported within the expertise of the lab and by access to the latest advanced technologies, including mass spectrometry, biochemistry, molecular biology, imaging, sequencing/bioinformatics and tissue culture. Emerging hypotheses will be investigated in mouse models. Essential to the project is collaboration with the brain cancer labs in the Cancer Research Scotland Centre in Glasgow and Edinburgh (Birch, Chalmers, Pollard). Our aim is to work together to develop therapeutic approaches for treating brain cancers.

The successful applicant will require a PhD in gene regulation, signalling research and/or neurons/brain cancers. Applications are welcomed from current PhD students, close to completing their degree. Previous experience in some of the areas mentioned above is advantageous but training in new areas of research is supported and encouraged. Mouse models will form an important part of the project.

For informal enquiries please email [email protected].

Postdoc support

Postdocs are key members of our research community, and we offer them a range of opportunities to train and develop as researchers while they are with us:

  • Exciting, innovative cancer research projects in state-of-the art labs
  • A highly collaborative and interactive research environment
  • Access to and training in key advanced technologies, for example imaging and in vivo modelling
  • A mentor enabling scheme to aid personal and professional development
  • A rich programme of scientific exchange through seminars, workshops and meetings
  • Support to make fellowship and small grant applications, including during their transition to their next position
  • Guidance and mentoring to compete for an independent scientist position as well as a multitude of other career options, including in industry.
  • A highly engaged postdoc forum, providing peer support, training, careers advice and regular social events
  • Equality, Diversity and Inclusion

    Our overarching research ethos at the Institute is about excellence, honesty, openness, accountability and integrity. The diversity of our staff and students is also what makes the Institute such a vibrant place to work and advance discoveries in cancer research. Family friendly policies, our collaborative ethos, a focus on good mental health and well-being and opportunities for all help to create an enjoyable and inclusive workplace where your voice matters.

    The Institute is also committed to increasing the number of female scientists at the postdoc level and beyond and encourages female applicants to apply. We have recently introduced a highly attractive maternity policy which provides 12-18 months support and funding for postdocs wishing to take time off to spend with their children amongst other family friendly policies

    Employee Benefits

  • Competitive salary
  • 40.5 days annual leave including bank holidays (pro-rata)
  • Defined Contribution pension scheme
  • Life Insurance scheme
  • Employee Assistance Programme
  • Season ticket loan
  • Additional maternity pay at 6 month's full pay (subject to service)
  • Shared parental leave
  • Cycle to work scheme that could save you 26-40% on a bike and accessories.
  • Access to Employee benefit schemes with discounts on supermarkets, cinema, travel and much more.
  • On-site secure parking
  • Closing Date: 9 June 2024 but we will contact promising candidates on a rolling basis, so please apply as soon as you are ready.

    Job details

    Title

    Postdoctoral Research Scientist - Prof Vicky Cowling

    Employer

    Cancer Research UK

    Location

    United Kingdom

    Published

    May 14, 2024

    Application deadline

    June 09, 2024

    Job type

    Postdoc

    Field

    Biology,Chemistry,Medicine,Physics

    About the employer

    Cancer Research UK is a cancer research and awareness charity in the United Kingdom and Isle of Man, formed on 4 February 2002 by the merger of The Cancer Research Campaign and the Imperial Cancer Research Fund. As the world's largest independent cancer research charity it conducts research by the charity's own staff and by its grant-funded researchers. It also provides information about cancer and runs campaigns aimed at raising awareness and influencing public policy.

    Cancer Research UK is the world’s leading charity dedicated to beating cancer through research. They have discovered new ways to prevent, diagnose and treat cancer that together have saved millions of lives across the world. Cancer Research UK has been at the heart of the progress that has already seen survival rates double in the last thirty years. But one in three of us will still get cancer at some point. Our groundbreaking work, funded entirely by the public (It raises money through donations, legacies, community fundraising, events, retail and corporate partnerships. Over 40,000 people are regular volunteers), will help ensure that millions more people will survive. Cancer Research UK works in partnership with others to achieve the greatest impact in the global fight against cancer. They provide life-changing information to anyone affected by cancer, run awareness initiatives so that cancer can be detected early, and help people reduce their risk of the disease. Their campaigning and lobbying keeps cancer at the top of the political agenda. Cancer Research UK became full UICC member in 1986.

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