Postdoctoral Research Associate
Department of Biology, South Parks Rd, Oxford, OX1 3RB
About the role
The arms race at the plant-pathogen interface is a fascinating field of biology that can deliver important new strategies for crop protection. Within this ERC-funded project, we used chemical proteomics to discover secreted plant proteins of Nicotiana benthamiana that are manipulated by Pseudomonas syringae during infection (e.g. Sueldo et al., New Phytol. 2024) and used artificial intelligence (e.g. Homma et al., Nat. Comm 2023) to predict pathogen proteins that might be responsible for this manipulation. This project aims to elucidate the molecular mechanisms underpinning extracellular manipulation of the host during infection. You will use co-immunoprecipitation to verify predicted protein-protein interactions and establish enzymatic assays and activity-based labelling to demonstrate the effect of target manipulation. You will use reverse genetics to deplete the components from both plant and pathogen to demonstrate their importance in pathogen virulence and plant immunity.
About you
We seek an enthusiastic new colleague who has extensive experience in molecular cloning, protein expression and purification, and who is keen to collaborate in an interdisciplinary research team.
How to apply
Applications should include the application letter, a CV, a list addressing the job criteria, and names of two academic references. Where Covid-19 has resulted in substantial disruption to your work or research outputs, please explain this by providing an additional paragraph in your supporting statement.
The University of Oxford is committed to equality and valuing diversity. All applicants will be judged on merit, according to the selection criteria.
This post is a 2-year fixed term, full time position.
The closing date for applications is 12.00 noon on 02 August 2024.
For further inquiries, please contact [email protected]
Contact Person : HR Team Vacancy ID : 173946 Contact Phone : Closing Date & Time : 02-Aug-2024 12:00 Pay Scale : STANDARD GRADE 7 Contact Email : [email protected] Salary (£) : £36,024 - £39,347 per annum
Job details
Title
Postdoctoral Research Associate
Employer
University of Oxford
Location
United Kingdom
Published
July 06, 2024
Application deadline
August 02, 2024
Job type
Postdoc
Field
Biology,Chemistry,Physics
About the employer
The University of Oxford is the oldest university in the English-speaking world, and is actually so ancient that its founding date is unknown – though it is thought that teaching took place there as early as the 11th century. It’s located in and around the medieval city center of Oxford, dubbed “the dreaming city of spires” by the 19th century poet Matthew Arnold, and comprises 44 colleges and halls as well as the largest library system in the UK.
There are 22,000 students at Oxford in total, around half of whom are undergraduates, while 40 per cent are international students. A quarter of the city of Oxford’s residents are students, giving the city the youngest population in the UK.
The University of Oxford does not have a main campus, its buildings and facilities instead being scattered around the medieval city center. Its colleges each have a distinctive character and traditions often dating back centuries. Colleges are self-governing institutions to which students usually apply directly. There are four academic divisions within Oxford University: Humanities, Mathematical, Physical and Life Sciences; Medical Sciences; and Social Sciences. The university’s particular strength is the sciences, and it is ranked number one in the world for medicine.
Oxford is a youthful and cosmopolitan city with plenty to see and do. There are dozens of historic and iconic buildings, including the Bodleian Libraries, Ashmolean Museum, Sheldonian Theatre, the cathedral, and the colleges themselves. Students can choose to spend their time studying or avail themselves of the many extracurricular activities available. There’s a strong musical life at Oxford, with clubs and societies spanning all genres, from jazz, through to classical and folk. Oxford is also ranked highly for sport, with its top rowers taking part every year in the world-famous boat race with the University of Cambridge on the River Thames. Drama lovers are also well catered for, with one of the largest and most vibrant university drama scenes in the country.
Oxford has an alumni network of over 250,000 individuals, including more than 120 Olympic medalists, 26 Nobel Prize winners, seven poets laureate, and over 30 modern world leaders (including Bill Clinton, Aung San Suu Kyi, Indira Ghandi and 26 UK Prime Ministers).
It has a friendly rivalry with Cambridge for the title of best university in the UK and is regularly ranked as being one of the top three universities in the world. Notable Oxford thinkers and scientists include Tim Berners-Lee, Stephen Hawking and Richard Dawkins.