Postdoctoral Research Associate Aston Pharmacy School Location: Aston University Main Campus
Salary: Grade 7/8 £29,605 to £42,155 Contract Type: Fixed Term (12 months)
Basis: Full Time Closing Date: 23.59 hours BST on Friday 22 September 2023 Interview Date: To be confirmed Reference: R230194 Release Date: Friday 15 September 2023
An exciting opportunity has arisen to join our dynamic multidisciplinary and collaborative translational epilepsy research community here at Aston. We are looking to appoint one outstanding research scientist to work in the group of Dr. Felix Chan (PI) in a funded project working on lysine metabolism in tuberous sclerosis complex. This project is a compelling research opportunity funded by a fellowship from the United States National Institute of Health (NIH) and Tuberous Sclerosis Alliance; thus, it will involve close communication and work opportunity with US-based investigators, funding agencies, and research stakeholders. This project forms a core part of the research at Dr. Chan's group to utilize metabolic-based approaches to develop new therapeutic approaches for pediatric epilepsy; of which in tuberous sclerosis complex (TSC), the severe epilepsy remains the top unmet clinical need.
The successful applicant will conduct metabolomics experiment using liquid- chromatography mass-spectrometry (LC-MS) on clinical samples obtained from a large cohort of TSC patients with epilepsy obtained through the NIH study consortium. In addition, the applicant will use induced pluripotent stem cell (iPSC) line from TSC patients and conduct CRISPR-gene editing to test our hypothesis of the involvement of lysine metabolism in epilepsy in TSC. Thus, knowledge of either LC-MS and/or iPSC tissue-culture technique would be a bonus. Appropriate training will be provided where required. There is also opportunity to expand and learn in vitro electrophysiology (patch clamp, multielectrode-array recording) within the remit of the group and project. Career development is at the core of this opportunity and so, the applicant will be encouraged to attend local, national, and international meetings; form and strengthen research network; and apply for independent funding opportunity. While this opportunity is fixed term for1 year, every avenue will be explored to provide additional duration of funding to maintain employment in this role.
We are keen to attract highly motivated individual with relevant research experience and training into this role. Collaboration and team-work is central to our research culture at Aston. Applicants will have a PhD in relevant neuroscience/biochemistry/molecular biology discipline. International applicants are welcome and we welcome individuals with interest in international collaborative research, with our US-based partners.
Informal enquiries about the position and/or projects can be made to Dr. Felix Chan at [email protected]
Aston University is committed to the principles of the Athena SWAN Charter https:// www. ecu.ac.uk/equality-charter-marks/athena-swan/, recognised by a bronze award. We pride ourselves on our vibrant, friendly, supportive working environment and collaborative atmosphere.
As users of the disability confident scheme, we guarantee to interview all disabled applicants who meet the minimum criteria for the vacancy.
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Aston University is an equal opportunities employer and welcomes applications from all sections of the community. It promotes equality and diversity in all aspects of its work. We strive to have robust inclusivity strategies in place, including race and sexual orientation, to encourage colleagues to have the confidence and freedom to be themselves in the workplace. For more information, visit: https: // www2.aston.ac.uk/about/inclusive-aston
We recognise the value of flexible working. Please contact the recruiting manager to discuss what flexible working options are available for particular roles.
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Job details
Title
Postdoctoral Research Associate (R230194)
Employer
Aston University
Location
United Kingdom
Published
September 16, 2023
Application deadline
September 22, 2023
Job type
Research
Field
Biology,Chemistry,Medicine,Physics
About the employer
Aston University is a leading public research university in the UK. Established in 1966, The university campus is located on a green 60 acre, self-contained site in the center of Birmingham. Aston University is an internationally acknowledged center for education and research endeavor. The university offers undergraduate, postgraduate, apprenticeship, foundation, and executive programs across disciplines. It also offers arrays of online courses. All the programs offered at the university are designed corresponding to the trends and demands of the industry and business globally.
The various faculties and schools of the university include Engineering & Applied Science, Aston Graduate School, Languages & Social Sciences, Aston Business School, Life & Health Sciences, and Aston Medical School. The team of faculty of Aston University comprises highly qualified professors as well as experts from respective industries. Modern tools and logical approaches like case studies are adopted in teaching methodologies. Besides theoretical sessions, the university gives emphasis on the practical training of students. Skill development programs are carried out to inculcate dexterity for leading-edge technologies among students.
Aston University boasts a world-class infrastructure at the campus offering the finest learning experience. There are hi-tech laboratories, libraries, studios, and IT centers, and seminar halls at the campus supporting an environment for advanced knowledge. Aston University is a hub for world-leading research initiatives. To undertake the highest quality of research, the university has established advanced research centers. 78% of the research has been evaluated ‘World-leading’ by Research Excellence Framework (REF) 2014. The university has teamed up with universities and research institutes across the world for knowledge sharing and collaborative research initiatives. Further, the university maintains partnerships with the industry for sponsored research programs.
Aston is a university of global repute. Students across the world come to study at a prestigious university. The university considers all the aspects of students. It provides counseling, medical, legal (VISA and other), and other services to students. There are indoor and outdoor sports arenas, fitness centers, swimming pools, cafeterias, banks, and other facilities at the campus.
The university offers modern accommodation facilities to students. There are various student clubs at the university that organizes sports meets, music fests, dance competitions, literary fest, art exhibitions, and other events. All these events comprise cross-disciplinary participation that helps to build team spirits among students. Aston University offers various scholarships and study loans to students so that all can have access to education beyond any financial barrier. Aston University maintains a high record of placements. Students passing from the university are recruited by leading companies with high remuneration packages.