Postdoctoral Research Associate/ Postdoctoral Research Fellow
Grade 6 £36,024 - £44,263 per year, Grade 7 £44,263 - £54,395 per year
Hours of work
University of York campus
To be confirmed
Job Description 12851 Grade 6.pdf (PDF, 336.99kb)
Job Description 12851 Grade 7.pdf (PDF, 337.78kb)
The aim of the lab, and this project, is to use insect synthetic biology to develop new, safe, sustainable methods for reducing the harm caused by pest insects, particularly mosquitoes and mosquito-borne disease. This position is part of a five-year £3m project (2023-2028), funded by the Wellcome Trust, led by Prof Luke Alphey at York; project partners include The Pirbright Institute (UK), University of Tartu (Estonia) and Universiti Malaya (Kuala Lumpur).
Better methods for controlling mosquito-borne viruses are urgently required. We will develop broad-spectrum anti-viral traits in engineered mosquitoes. By “broad-spectrum” we mean active against multiple arboviruses, in contrast to the current state-of-the-art for synthetic anti-viral (“reduced vector competence”) traits, RNAi-based systems which provide resistance only against specific viruses or virus strains.
Such tools could be delivered to wild vector populations via mating between released modified mosquitoes and wild mosquitoes, possibly in combination with “gene drives” - the target of another project team in the lab. These methods are egalitarian – everyone within the protected area is equally protected, irrespective of wealth, ethnicity, gender, education etc.
The project focuses on alphaviruses, and the use of super-infection exclusion to provide broad-spectrum protection. The core of the project is to develop and test components, modules and systems for these novel anti-viral “refractory insect” systems in Aedes aegypti. There are two positions is available at either Grade 7, Research Fellow or Grade 6, Postdoctoral Research Associate level or, potentially, one at each grade.
Nominal start date is Jan 2023, but negotiable. It is anticipated that additional roles with later start dates will become available, across a range of grades, for which informal enquiries may be made to [email protected].
Postdoctoral Research Associate - The role is insect genetic studies (responsible for design and development of new transgenic/gene edited strains, rearing and colony maintenance, phenotypic analysis, experimental design and statistical analysis). Additional responsibilities include molecular biology (assisting with design and development of novel plasmids, preparing DNA for mosquito injections, molecular analysis of transgenic strains), communicating progress and data including assisting with manuscript preparation, and training/supervising other staff/students as required.
Research Fellow – as above but with additional responsibility for leading the project team.Skills, Experience & Qualification needed
Interview date : To be confirmed
For informal enquiries: please contact Prof Luke Alphey ([email protected])
The University strives to be diverse and inclusive – a place where we can ALL be ourselves.
We particularly encourage applications from people who identify as Black, Asian or from a Minority Ethnic background, who are underrepresented at the University.
We offer family friendly, flexible working arrangements, with forums and inclusive facilities to support our staff. #EqualityatYork
Postdoctoral Research Associate/ Postdoctoral Research Fellow
University of York
November 14, 2023
December 10, 2023
About the employer
The University of York was established in 1963 when the University Grants Commission permitted a university in 1960. The university started operating with its first batch of 230 students on Oct. 9, 1963, under the leadership of Lord James as its chancellor. Originally the university only had 28 staff members and six departments; economics, English, education, history, politics, and mathematics. At present, the university includes nine colleges and more than 30 research centers and academic departments. The university is now accredited by the Privy Council.
Located in Heslington, the University of York has been improving and expanding its campus ever since its establishment. The campus has plenty of landmarks, sculptures, and college buildings. The King's Manor is a historic structure that currently houses the Centre for Medieval Studies, the Centre for Eighteenth-Century Studies, and the Department of Archaeology. Located in the center of the campus, Central Hall is a tiered auditorium used for hosting concerts, competitions, conferences, graduations, fashion shows, and other events. The university's archives and library network includes many libraries on the campus and in the nearby area. The JB Morrell library is the campus' main library. Heslington Hall is another significant landmark of the campus.
The University of York offers a plethora of undergraduate, research, and postgraduate programs in various fields like archaeology, sciences, computer science, law, management, medicine, mathematics, languages, arts, philosophy, psychology, and sociology. The university has 18,930 students. The university has collaborations with reputed research-oriented institutions across the world. It is a part of an alliance of 24 well-established research-intensive universities. Also, the university has great student exchange programs and research links with numerous other universities around the globe. It offers excellent professional training to its students and provides them outstanding employment opportunities in prestigious firms.
The university has produced several notable and successful alumni. Greg Dyke is a renowned British journalist, media executive, broadcaster, and football administrator. Aníbal Cavaco Silva is Portugal's former president. Mahmoud Mohieldin is the vice-president of the World Bank Group. Jung Chang is a British writer, famous for her award-winning book 'Wild Swans'. Anthony Horowitz is an English screenwriter and novelist, popular for his works such as 'The Diamond Brothers' series, 'The Power of Five' series, and the 'Alex Rider' series. Han Seung-soo is South Korea's former prime minister. Peter Hitchens is an author and journalist who writes for The Mail. His popular works include 'The Abolition of Britain', 'The War We Never Fought', and 'The Rage Against God'. Many other distinguished people are a part of the university's alumni network.