University of Exeter

University of Exeter

Postdoctoral Research Associate or Fellow

United Kingdom

Closing in 17 days

Job details

Job reference

P92020

Date posted

08/02/2024

Application closing date

10/03/2024

Location

Exeter

Salary

The starting salary will be from £32,982 to £38,205 on Grade E for the Postdoctoral Associate role and from £41,732 to £51,283 on Grade F for the Postdoctoral Research Fellow role, depending on qualifications and experience.

Package

Generous holiday allowances, flexible working, pension scheme and relocation package (if applicable).

Contractual hours

36.5

Basis

Full-time

Job category/type

Research

Attachments

Job/description/P92020 - PDRF.pdf Job/description/P92020 - PDRA.pdf
Postdoctoral Research Associate or Fellow

Job description

Faculty of Health and Life Sciences

This new full-time post is available from 1 April 2024 until 31 March 2026 on a fixed term basis.

The post

The Faculty wishes to recruit a Postdoctoral Research Associate or Postdoctoral Research Fellow to participate in the work of Dr Vicki Gold, Dr Remy Chait and Dr Tobias Bergmiller. This Leverhulme Trust funded post is available from 1 April 2024 until 31 March 2026. The successful applicant will investigate the lifecycle of a filamentous phage using a combination of fluorescence light microscopy, single-cell microfluidics and electron cryo- microscopy (cryoEM). Further details of our work can be found in the following publications:

Conners R, León-Quezada RI, McLaren M, Bennett NJ, Daum B, Rakonjac J & Gold VAM. Cryo-electron microscopy of the f1 filamentous phage reveals insights into viral infection and assembly. Nat Commun (2023).

doi: 10.1038/s41467-023-37915-w.

Bergmiller, T., Andersson, A. M. C., Tomasek, K., Balleza, E., Kiviet, D. J., Hauschild, R., Tkačik, G. & Guet, C . C. Biased partitioning of the multidrug efflux pump AcrAB-TolC underlies long-lived phenotypic heterogeneity. Science (2017).

doi: 10.1126/science.aaf4762.

Nikolic, N., Anagnostidis, V., Tiwari, A., Chait, R. & Gielen, F. Droplet- based methodology for investigating bacterial population dynamics in response to phage exposure. Frontiers in Microbiology (2023).

doi: 10.3389/fmicb.2023.1260196

The post will include:

  • Bacterial cell culture, cloning, protein purification and labelling
  • Development and use of microfluidic devices and techniques for single-cell fluorescence microscopy.
  • Sample preparation for electron microscopy (negative stain and cryo)
  • High-resolution data collection and processing
  • About you

    PDRA: The successful applicant will be able to present information on research progress and outcomes, communicate complex information, orally, in writing and electronically and prepare proposals and applications to external bodies.

    Applicants will possess a relevant PhD in in Biochemistry/Biological Sciences (or nearing completion) or possess an equivalent qualification/experience in a related field of study and be able to demonstrate sufficient knowledge in the discipline and of research methods and techniques to work within established research programmes.

    Candidates will be expected to be motivated and demonstrate good knowledge of the topic, possess excellent problem solving, interpersonal and communication skills and a collaborative spirit, combined with an ability to think carefully about their research. Experience of electron-cryo microscopy and image processing would be a strong advantage.

    PDRF: The successful applicant will be able to develop research objectives, projects and proposals; identify sources of research funding and contribute to the process of securing funds and make presentations at conferences and other events.

    Applicants will possess a relevant PhD in Biochemistry/Biological Sciences or equivalent qualification/experience in a related field of study. The successful applicant will be a nationally recognised authority in the subject area and possess sufficient specialist knowledge in the discipline to develop research programmes and methodologies. The successful applicant will also be able to work collaboratively, supervise the work of others and act as team leader as required.

    Candidates will be expected to be motivated and demonstrate good knowledge of the topic, possess excellent problem solving, interpersonal and communication skills and a collaborative spirit, combined with an ability to think carefully about their research. The successful applicant will also be able to supervise the work of others as required. Experience of electron-cryo microscopy and image processing would be a strong advantage.

    In addition, the candidate will:

  • possess a keen interest and desire to learn/advance skills in fluorescence microscopy, single-cell microfluidics and electron cryo-microscopy
  • be familiar with standard microbiology, molecular biology and biochemical techniques including the use of fluorescent probes
  • have a publication record commensurate with experience
  • possess good time management skills and the ability to prioritise and work independently
  • Please ensure you read the Job Description and Person Specification for full details of this role.

    What we can offer you

  • Freedom (and the support) to pursue your intellectual interests and to work creatively across disciplines to produce internationally exciting research;
  • Support teams that understand the University wide research and teaching goals and partner with our academics accordingly
  • An Innovation, Impact and Business directorate that works closely with our academics providing specialist support for external engagement and development
  • Our Exeter Academic initiative supporting high performing academics to achieve their potential and develop their career

  • A multitude of staff benefits including sector leading benefits around maternity, adoption and shared parental leave (up to 26 weeks full pay), Paternity leave (up to 6 weeks full pay), and a new Fertility Treatment Policy

  • A beautiful campus set in the heart of stunning Devon.

  • The University of Exeter

    We are a member of the prestigious Russell Group of research-intensive universities and in the top 200 universities in the world (Times Higher Education World University Rankings 2024 and QS World University Ranking 2024). We combine world-class teaching with world-class research, achieving a Gold rating in the Teaching Excellence Framework Award 2023, underpinned by Gold ratings for Student Experience and Student Outcomes.

    Our world-leading research impact has grown more than any other Russell Group university in recent years, and we are home to some of the world's most influential researchers, seeking to answer some of the most fundamental issues facing humankind today. More than 99 percent of our research is of international quality and 47 percent is world-leading (2021 Research Excellence Framework).

    We encourage proactive engagement with industry, business and community partners to enhance the impact of research and education and improve the employability of our students. Read about our world leading research – Green Futures and how we are transforming education for a changing world. We are located in a beautiful part of the country and Exeter (a fast growing tech hub) is one of only a few UK cities to have been designated as a UNESCO Creative City

    Our Equality, Diversity and Inclusion Commitment

    We are committed to ensuring reasonable adjustments are available for interviews and workplaces.

    Whilst all applicants will be judged on merit alone, we particularly welcome applications from groups currently underrepresented within our working community.

    With over 30,000 students and 7,000 staff from 150 different countries we offer a diverse and engaging environment where our diversity is celebrated and valued as a major strength. We are committed to creating an inclusive culture where all members of our community are supported to thrive; where diverse voices are heard through our engagement with evidence-based charter frameworks for gender (Athena SWAN and Project Juno for Physics), race equality (Race Equality Charter Mark), LGBTQ+ inclusion (Stonewall Diversity Champion) and as a Disability Confident employer.

    Further Information

    For further information please contact Dr Vicki Gold, e-mail [email protected] or telephone (01392) 727455.

    Job details

    Title

    Postdoctoral Research Associate or Fellow

    Employer

    University of Exeter

    Location

    United Kingdom

    Published

    February 09, 2024

    Application deadline

    March 10, 2024

    Job type

    Postdoc

    Field

    Agricultural Science,Biology,Chemistry,Physics

    About the employer

    The University of Exeter is a public university that focuses on research. It was established in the year 1955. In 1851, it was first formed as Schools of Science and Art. In 1900, its name was then changed to the Royal Albert Memorial College which later converted into a university college of the southwest in the year 1922. And finally, it received its authorization in 1955 as the University of Exeter.

    The university is a part of the Russell Group which contains the top research-intensive universities of United Kingdom and has a total of 3 campuses. Out of all 3, Streatham is the largest campus by area as it contains most of the university's executive buildings.

    Also, it is considered as one of the most beautiful buildings in the nation. Moreover, the Penryn campus is associated with Falmouth University as per a combined initiative.

    The University has more than 25,263 student population who are coming from over 130 different nations. The university organizes its educational and administrative departments into 6 scholastic colleges. There are many research centres and institutes inside the campus. There are more than 200 student societies including creative writing, theatre club, Socialist Students societies, Poker Society and Conservative Future society. The university maintains an athletic union which is responsible for organizing and administrating all the sports activities fairly and actively. The union governs more than 50 sports clubs which have around 5,000 students.

    The university has a great alumni base and actively connects with more than 125,000 alumni in 183 countries across the world. The graduates have been working in different fields. From globally known business leaders and lawyers to inspiring leaders and teachers to highly praised members of the press and artists, this university has proudly touched the lives of its alumni. Some of the much-known alumni of the university are J.K. Rowling (author- famous for Harry Potter series), Ameenah Gurib (Mauritius's 6th President) and Abdullah Gül (Turkey's 11th President).

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