University of Oxford

University of Oxford

Postdoctoral Research Associate in Chemistry

Postdoctoral Research Associate in Chemistry

Department of Chemistry, Kavli Institute for Nanoscience Discovery, New Biochemistry Building, South Parks Road, Oxford, OX1 3QU

We are looking for a Postdoctoral Research Associate who would like to be part of our project on single molecule proteomics , through nanometric analyses for a period of up to three years. The project, which has been awarded £5.5m by the BBSRC, involves a multidisciplinary team in Oxford, Liverpool and Cambridge and is led by Professor Justin Benesch. The team you will be part of aims to develop and apply a novel approach for identifying proteins and their common modifications. Seemingly subtle protein modifications, such as phosphorylation, can drastically alter a protein's function. However, these modifications are difficult to detect with existing technology – meaning they remain largely hidden. The new approach will help scientists to better understand how proteins function in health and disease.

This role will be based in the Department of Chemistry and will integrate into the team working on this project that are under the collective direction of Profs Benesch, Aarts, Bayley, Krishnan, Kukura, and Qing. The team is focussed on the integration of three main technologies (nanopore sensing, mass photometry, and escape-time electrometry) to perform multidimensional analyses of proteins, ultimately performing single molecule measurements of mass, charge, and chemical profiles in a complex biological mixtures.

This position is motivated by the fact that integration of these technologies requires the development of novel micro- and nanofluidic approaches. You will design and fabricate micro/nanofluidic devices in Si, glass and PDMS using cleanroom-based nanofabrication processes and demonstrate their operation using single molecule optical microscopy and electrical measurements.

About you:

Applicants must hold a PhD in Physics, Chemistry, or a related area or be close to completion, prior to taking up your appointment. You should have experience in working in clean-room environments and be experienced in microfluidic device design and fabrication as well as clean-room workflows. You should be able to demonstrate interest in developing new technologies for single molecule measurements of biological molecules and a basic knowledge in single molecule optical microscopy or electrochemistry. You will join a growing interdisciplinary team and be expected to contribute to the day-to-day operation of the cleanroom facility, training of new users and assisting with the development of new fabrication processes.

You will be expected to manage your own academic research and administrative activities. This involves small scale project management, co-ordinating multiple aspects of work to meet deadlines.

Applications are welcome from candidates who don't currently have the right to work in the UK, but who would be eligible to obtain a visa.

Application Process :

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your application. In your supporting statement, please explain how you meet each of the selection criteria found in the job description.

Certificates, references and research papers should not be provided at this stage.

As part of the online application, you will be required to upload a CV, and a supporting statement ( <5 pages) setting out how you meet the selection criteria and your reasons for interest in this particular post.

The closing date for applications is 12.00 midday, 23 May 2024 UK time. Interviews will be held as soon as possible thereafter.

The University of Oxford and The Department of Chemistry are Silver Athena SWAN holders. Applications are particularly welcome from women and black and ethnic minority candidates, who are under-represented in Chemistry research posts in Oxford.

Contact Person : Recruitment Vacancy ID : 172729 Contact Phone : Closing Date & Time : 23-May-2024 12:00 Pay Scale : STANDARD GRADE 7 Contact Email : [email protected] Salary (£) : £36,024 - £38,205 per annum

Job details

Title

Postdoctoral Research Associate in Chemistry

Employer

University of Oxford

Location

United Kingdom

Published

May 03, 2024

Application deadline

May 23, 2024

Job type

Postdoc

Field

Agricultural Science,Chemistry,Physics,Space Science

About the employer

The University of Oxford is the oldest university in the English-speaking world, and is actually so ancient that its founding date is unknown – though it is thought that teaching took place there as early as the 11th century. It’s located in and around the medieval city center of Oxford, dubbed “the dreaming city of spires” by the 19th century poet Matthew Arnold, and comprises 44 colleges and halls as well as the largest library system in the UK. 

There are 22,000 students at Oxford in total, around half of whom are undergraduates, while 40 per cent are international students. A quarter of the city of Oxford’s residents are students, giving the city the youngest population in the UK. 

The University of Oxford does not have a main campus, its buildings and facilities instead being scattered around the medieval city center. Its colleges each have a distinctive character and traditions often dating back centuries. Colleges are self-governing institutions to which students usually apply directly. There are four academic divisions within Oxford University: Humanities, Mathematical, Physical and Life Sciences; Medical Sciences; and Social Sciences. The university’s particular strength is the sciences, and it is ranked number one in the world for medicine.

Oxford is a youthful and cosmopolitan city with plenty to see and do. There are dozens of historic and iconic buildings, including the Bodleian Libraries, Ashmolean Museum, Sheldonian Theatre, the cathedral, and the colleges themselves.  Students can choose to spend their time studying or avail themselves of the many extracurricular activities available. There’s a strong musical life at Oxford, with clubs and societies spanning all genres, from jazz, through to classical and folk. Oxford is also ranked highly for sport, with its top rowers taking part every year in the world-famous boat race with the University of Cambridge on the River Thames. Drama lovers are also well catered for, with one of the largest and most vibrant university drama scenes in the country.

Oxford has an alumni network of over 250,000 individuals, including more than 120 Olympic medalists, 26 Nobel Prize winners, seven poets laureate, and over 30 modern world leaders (including Bill Clinton, Aung San Suu Kyi, Indira Ghandi and 26 UK Prime Ministers). 

It has a friendly rivalry with Cambridge for the title of best university in the UK and is regularly ranked as being one of the top three universities in the world. Notable Oxford thinkers and scientists include Tim Berners-Lee, Stephen Hawking and Richard Dawkins.

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