9 May 2023

Job Information

Organisation/Company

Biofyzikální ústav Akademie věd ČR, v. v. i.

Research Field

Biological sciences » Biology

Researcher Profile

First Stage Researcher (R1)

Country

Czech Republic

Application Deadline

30 May 2023 - 23:59 (Europe/Prague)

Type of Contract

To be defined

Job Status

Full-time

Hours Per Week

40

Offer Starting Date

1 Jun 2023

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Open postdoctoral position at Institute of Biophysics of the Czech Academy of Science in Brno, Czech Republic

Are you a recent PhD graduate in molecular and cell biology, biochemistry, or biophysics looking for an exciting postdoctoral opportunity? Join our team for a project aimed at investigating the function of Haspin kinase and its role in the regulation of cell cycle, plasticity, and fate.

We are seeking a highly motivated and enthusiastic candidate with a PhD in the relevant fields. Prior postdoctoral experience is not required; we welcome candidates who are eager to learn and have a strong passion for research. Good communication skills and the ability to collaborate with multiple teams are also important.

As a postdoctoral researcher on our team, you will have the opportunity to use advanced proteomics and unique chemical probes to study the Haspin interactome and its function in different stages of the cell cycle. You will also investigate the role of Haspin in plasticity regulation and cell fate decision making, and evaluate its potential as a therapeutic target.

If you are interested in this opportunity, please send your CV, cover letter, and contact information for at least three referees to Karel Souček at [email protected]. We welcome all applicants who are interested in joining our team and embarking on an exciting research journey with us.

RECENT PUBLICATIONS:

Kvokackova, B., et al. Single-cell protein profiling defines cell populations associated with triple-negative breast cancer aggressiveness. Mol Oncol , 2022.

Muresan XM, et al: Toll-like receptor 3 (TLR3) overexpression induces invasion of prostate cancer cells, whereas its activation triggers apoptosis. Am J Pathol 2022.

Drapela S, et al.: High-Throughput, Parallel Flow Cytometry Screening of Hundreds of Cell Surface Antigens Using Fluorescent Barcoding. Apoptosis and Cancer: Methods and Protocol. Edited by Barcenilla H, Diaz D. New York, USA: Springer Nature, 2022.

Remsik J, et al.: TGF-beta regulates Sca-1 expression and plasticity of pre-neoplastic mammary epithelial stem cells. Sci Rep 2020, 10:11396.

Drapela S, et al.: The CHK1 inhibitor MU380 significantly increases the sensitivity of human docetaxel-resistant prostate cancer cells to gemcitabine through the induction of mitotic catastrophe. Mol Oncol 2020, 14:2487-503.

Requirements

Research Field

Biological sciences » Biology

Education Level

PhD or equivalent

Languages

ENGLISH

Level

Excellent

Additional Information Work Location(s)

Number of offers available

1

Company/Institute

Biofyzikální ústav Akademie věd ČR, v. v. i.

Country

Czech Republic

State/Province

Czech republic

City

Brno

Postal Code

61200

Street

Kralovopolská 2590/135

Where to apply

E-mail

[email protected]

Contact

State/Province

Czech republic

City

Brno

Website

https: // www. ibp.cz/

Street

Královopolská 2590/135

Postal Code

61200

E-Mail

[email protected]

STATUS: EXPIRED