13 Nov 2023

Job Information

Organisation/Company

CNRS

Department

Institut Jacques Monod

Research Field

Physics

Researcher Profile

Recognised Researcher (R2)

Country

France

Application Deadline

1 Dec 2023 - 23:59 (UTC)

Type of Contract

Temporary

Job Status

Full-time

Hours Per Week

35

Offer Starting Date

1 Apr 2024

Is the job funded through the EU Research Framework Programme?

Not funded by an EU programme

Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Managing a research project Objective: creating a Vibrio cholerae strain adapted to DnaC, tracing the modifications and their succession during adaptation to DnaC to understand the mechanism underlying bidirectional replication initiation.

- Setting up the evolutionary screen assay - Construction of the screen strain - Construction of the plasmids of complementation - Building a viable screen strain - Steady state culture of cells and selection of cells with improved fitness - Whole genome sequence of adapted cells - Bioinformatics to identify the adaptive mutations

The host team The team comprises 3 permanent positions and 3 PhD students, working on the initiation of replication in vertebrates (human, chicken) and bacteria (Vibrio cholerae, Escherichia coli). The project will be supervised by Jean- Luc Ferat who is a professor at University Paris Cité.

The IJM The Institut Jacques Monod is a joint research unit of CNRS and Université Paris Cité. The Institute is ideally located on the left bank of Paris. The institute is a fundamental research center with some thirty groups covering the fields of genome and chromosome dynamics, cell dynamics and signaling, development and evolution with a rich scientific life.

Requirements

Research Field

Physics

Education Level

PhD or equivalent

Languages

FRENCH

Level

Basic

Research Field

Physics

Years of Research Experience

1 - 4

Additional Information

Eligibility criteria

- Molecular biology (needed) - Genetics (needed) - Bioinformatics (would be a plus – formation possible) - Evolutionary biology (would be a plus) - Cytology (would be a plus)

Website for additional job details

https: // emploi.cnrs.fr/Offres/CDD/UMR7592-JEAFER-002/Default.aspx

Work Location(s)

Number of offers available

1

Company/Institute

Institut Jacques Monod

Country

France

City

PARIS 13

Where to apply

Website

https: // emploi.cnrs.fr/Candidat/Offre/UMR7592-JEAFER-002/Candidater.aspx

Contact

City

PARIS 13

Website

https:// www. ijm.fr/

STATUS: EXPIRED