The University of Adelaide

The University of Adelaide

NHMRC Grant-Funded Researcher A

Australia

Closing in 11 days

(Level A) $75,888 to $102,040 per annum plus an employer contribution of 17% superannuation applies.

Fixed term, full time position available for 24 months.

We are looking to employ a full-time postdoctoral researcher for a research project funded by the National Health and Medical Research Council (NHMRC) in the field of genetic epidemiology/statistical genetics. This is a 2-year position, with the possibility of extension subject to satisfactory performance.

The successful candidate will be responsible for developing and applying statistical and computational approaches to interrogate large-scale genomic datasets to identify genes, proteomic markers and pathways underlying treatment response, resistance and side effects in patients with psychiatric disorders. The primary focus will be on the development of polygenic scores in large datasets, including in the UK Biobank (N=500,000), US All of Us Program data (N~1 million), and ConLiGen Consortium (N~3,000) data. There is also interest in developing multi-trait polygenic scores and using them across a wide range of complex phenotypes.

Specific activities include:

  • Develop polygenic scores and integrate them with other omics and clinical datasets to predict treatment outcomes in patients with psychiatric disorders.
  • Apply statistical models, e.g. using machine learning techniques, to improve the accuracy of predictions for polygenic risk scores in psychiatric patients.
  • Conducting quantitative genomic analyses of complex traits using various genomics and omics data sources such as the UK Biobank and the US All of Us Program.
  • Conducting genome-wide association studies (GWAS), transcriptome-wide association studies (TWAS), proteomics analyses, follow-up analysis, and interpreting research findings while preparing manuscripts for publication in scientific journals.
  • To be successful you will need:

  • A PhD (or near completion of PhD) in genetic epidemiology/epidemiology, statistics/biostatistics, computer science, computational biology, Quantitative Genetics, bioinformatics, or a closely related quantitative data-intensive field.
  • Demonstrated computational skills and experience in R, Python, Jupyter, Notebook, and genetic/genomic tools (e.g., PLINK2, GCTA, MR, FUMA).
  • Experience with big data analytics within Linux and cloud computing environments, and with data integration across multi-omics data.
  • Preference will be given to applicants with a publication track record relative to the opportunity.
  • Strong communication & writing skills.
  • This position requires a valid National Police Clearance Check.

    Enjoy an outstanding career environment

    The University of Adelaide is a uniquely rewarding workplace. The size, breadth and quality of our education and research programs - including significant industry, government and community collaborations - offers you a vast scope and opportunity for a long, fulfilling career.

    It also enables us to attract high-calibre people in all facets of our operations, ensuring you will be surrounded by talented colleagues, many world-leading. Our work's cutting-edge nature - not just in your own area, but across virtually the full spectrum of human endeavour - provides a constant source of inspiration.

    Our culture is one that welcomes all and embraces diversity consistent with our Staff Values and Behaviour Framework and our Values of integrity, respect, collegiality, excellence and discovery. We firmly believe that our people are our most valuable asset, so we work to grow and diversify the skills, knowledge and capability of all our staff.

    We embrace flexibility as a key principle to allow our people to manage the changing demands of work, personal and family life.

    In addition, we offer a wide range of attractive staff benefits. These include: salary packaging; flexible work arrangements; high-quality professional development programs and activities; and an on-campus health clinic, gym and other fitness facilities.

    Learn more at: adelaide.edu.au/jobs

    Your faculty's broader role

    The Faculty of Health and Medical Sciences contains one of Australia's largest concentrations of leading health researchers, teachers and clinical titleholders. It's comprised of eight schools and a number of specialist disciplines, institutes and centres, variously focused on world-class research, and training the next generation of: medical doctors; surgeons; dentists; nurses; psychiatrists; psychologists; and other health professionals.

    Learn more at: health.adelaide.edu.au

    If you have the talent, we'll give you the opportunity. Together, let's make history.

    Click on the ‘Apply Now' button to be taken through to the online application form. Please ensure you submit a cover letter, resume, and upload a document that includes your responses to all of the selection criteria for the position as contained in the position description or selection criteria document.

    Applications close 11:55pm, 9th June 2024.

    The University reserves the right to close this advertisement before the closing date if a suitable candidate is identified.

    For further information

    For a confidential discussion regarding this position, contact:

    Dr Azmeraw Amare NHMRC Emerging Leadership Fellow E: [email protected]

    You'll find a full position description and/or selection criteria below: (If no links appear, try viewing on another device)

    The University of Adelaide is an Equal Employment Opportunity employer committed to providing a working environment that embraces and values diversity and inclusion. Female applicants, people with a disability and/or and Aboriginal and Torres Strait Islander people who meet the requirements of this position are strongly encouraged to apply. If you have any support or access requirements, we encourage you to advise us at time of application.

    Download the Position Description Apply now

    Job details

    Title

    NHMRC Grant-Funded Researcher A

    Employer

    The University of Adelaide

    Location

    Australia

    Published

    May 09, 2024

    Application deadline

    June 09, 2024

    Job type

    Postdoc,Research

    Field

    Biology,Computer Science,Mathematics,Medicine

    About the employer

    The University of Adelaide (informally Adelaide University) is a public research university located in Adelaide, South Australia. Established in 1874, it is the third-oldest university in Australia. The university's main campus is located on North Terrace in the Adelaide city centre, adjacent to the Art Gallery of South Australia, the South Australian Museum and the State Library of South Australia.

    The university has four campuses, three in South Australia: North Terrace campus in the city, Roseworthy campus at Roseworthy and Waite campus at Urrbrae, and one in Melbourne, Victoria. The university also operates out of other areas such as Thebarton, the National Wine Centre in the Adelaide Park Lands, and in Singapore through the Ngee Ann-Adelaide Education Centre.

    The University of Adelaide is composed of five faculties, with each containing constituent schools. These include the Faculty of Engineering, Computer, and Mathematical Sciences (ECMS), the Faculty of Health and Medical Sciences, the Faculty of Arts, the Faculty of the Professions, and the Faculty of Sciences. It is a member of the Group of Eight and the Association of Commonwealth Universities. The university is also a member of the Sandstone universities, which mostly consist of colonial-era universities within Australia.

    The university is associated with five Nobel laureates, constituting one-third of Australia's total Nobel Laureates, and 110 Rhodes scholars. The university has had a considerable impact on the public life of South Australia, having educated many of the state's leading businesspeople, lawyers, medical professionals and politicians. The university has been associated with many notable achievements and discoveries, such as the discovery and development of penicillin, the development of space exploration, sunscreen, the military tank, Wi-Fi, polymer banknotes and X-ray crystallography, and the study of viticulture and oenology.

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